Keywords: Psychiatric Disorders, fMRI (resting state), anxiety disorders
Motivation: It is necessary to clarify the neurobiological mechanisms of anxiety disorders (ADs) to provide a unique biomarker for diagnosing ADs, facilitating accurate clinical diagnosis and targeted therapeutic interventions.
Goal(s): The primary objective is to elucidate the specific abnormalities in individuals with ADs' amygdala-based whole-brain connectivity.
Approach: The coordinate-based meta-analysis was conducted to find amygdala resting-state functional connectivity in patients with ADs. Furthermore, subgroup analysis was performed to explore potential functional lateralization.
Results: Distinct functional connectivity abnormalities were found in ADs, which provides a reference for diagnosing ADs.
Impact: These findings not only enhance our understanding of the underlying pathophysiological mechanisms in ADs but also may be valuable for the prevention, diagnosis and intervention of ADs.
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