Keywords: Heart Failure, Cardiomyopathy
Motivation: 31P heart applications can be used to monitor cardiac energetics, treatment response in vivo and metabolic inflexibility, a key feature of the failing heart.
Goal(s): We present here a 7T and 3T protocol for 31P heart application, including the validation of a dipole array coil design.
Approach: We evaluated the performance of the coil at 7T with B1 maps and through in vivo scans of 8 healthy with a long 31P CSI protocol, and tested the 3T protocol on 5.
Results: Results show spectra of excellent quality. PCr/gATP ratios lie within the expected range and B1+ maps show good uniformity.
Impact: This coil design has the potential of lifting the current limitations associated with the wider use of 31P cardiac MRSI to study the heart energetics. It can also help the diagnosis and the design of new drugs in the future.
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