Keywords: Myocardium, Contrast Agent, manganese-enhanced MRI
Motivation: Manganese-enhanced MRI (MEMRI) appears to be an interesting alternative to late-gadolinium enhancement (LGE) since manganese ions can enter cardiomyocytes through calcium channels, thus allowing intracellular characterization of living cells.
Goal(s): This study aims to evaluate the sensitivity of 3D-MEMRI for the characterizing MI scars heterogeneity compared to the clinical gold standard LGE.
Approach: Manganese has a long retention time in cardiomyocytes, allowing a longer acquisition time exploited to improve the spatial resolution of 3D MR images (~1 mm3 isotropic).
Results: This study confirms the potential of 3D-MEMRI as a more specific method than the clinical gold standard LGE for characterizing MI scars heterogeneity.
Impact: The ability of high-resolution 3D manganese-enhanced MRI (3D-MEMRI) to produce a finer characterization of the heterogeneity of the scar constitutes an important step forward in the management of myocardial infarction in the context of cardiac arrhythmias
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords