Keywords: Heart Failure, Dementia, Myocardial strains
Motivation: The mechanism of heart failure()-induced brain alterations is unclear
Goal(s): To investigate the alterations in brain structure in patients with HF and their relationship with cardiac dysfunction and cognitive impairment.
Approach: Using CAT12 to analyze intergroup differences in cortical thickness between HF patients and healthy controls, correlation analyses were performed to assess cortical thickness and cognitive impairment, cardiac dysfunction
Results: Reduced cortical thickness in patients with HF and correlation of reduced cortical thickness with cognitive impairment and cardiac dysfunction
Impact: Decreased cortical thickness in HF patients may play a mediating role between cardiac dysfunction and cogntive impairment.And our findings provide imaging evidence of brain alterations in HF patients.
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