Keywords: Myocardium, Diffusion Tensor Imaging
Motivation: The non-invasive imaging evaluation of myocyte disarray in hypertrophic cardiomyopathy (HCM) is still challenging.
Goal(s): We aimed to explore the myocardial microstructural characteristics of HCM by in-vivo cardiac diffusion tensor imaging (cDTI).
Approach: We prospectively enrolled thirty-five HCM patients and fifteen healthy controls for cDTI at 3.0T scanner.
Results: Myocardial disarray and abnormal microstructural dynamics of HCM can be characterized by in vivo cDTI. Moreover, cDTI allows early identification of myocardial microstructural changes, even before cardiovascular magnetic resonance (CMR) signs of fibrosis and hypertrophy.
Impact: Our findings shed light on the potential of cDTI for the early detection of myocyte disarray, further improving the value of CMR in the non-invasive myocardial tissue characterization of HCM.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords