Keywords: Data Processing, Contrast Agent
Motivation: Late Gadolinium Enhancement (LGE) imaging is the gold-standard CMR imaging for distinguishing heart tissue viability. However, not all patients can receive gadolinium-based contrast agent. Native T1 have been proposed in place of LGE.
Goal(s): This study explores pre-contrast cardiac MRF T1 and T2 measurements as potential indicators of ischemic myocardial scar.
Approach: Native T1 and T2 values were measured using cMRF in eleven ischemic patients using ROIs in both scar and non-scar myocardial tissue identified through LGE imaging.
Results: Native cMRF measurements differ between scar and non-scar areas. Synthetic images from these maps highlight scar tissue, offering a potential LGE imaging alternative.
Impact: Native cMRF T1 and T2 maps and synthetic images derived from these maps may enable differentiation of scar tissue from viable myocardium without the need for gadolinium-based contrast agents.
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