Abstract #1852

Longitudinal reproducibility of 3D-FID-CRT-MRSI in the human brain at 3T and 7T

Zeinab Eftekhari^1,2, Thomas B Shaw^1,3, Korbinian Eckstein^3,4, Bernhard Strasser⁴, Fabian Niess⁴, Lukas Hingerl⁴, Wolfgang Bogner⁴, and Markus Barth^1,2,3

¹Centre for Advanced Imaging, The University of Queensland, Brisbane, Australia, ²ARC Training Centre for Innovation in Biomedical Imaging Technology (CIBIT), The University of Queensland, Brisbane, Australia, ³School of Electrical Engineering and Computer Science, The University of Queensland, Brisbane, Australia, ⁴High-field MR Centre, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria

Synopsis

Keywords: Spectroscopy, Spectroscopy, 3D-FID-CRT-MRSI, 3T and 7T, Longitudinal Reproducibility, High-Field MRI, Ultrahigh-Field MRI, Magnetic Resonance Spectroscopy Imaging

Motivation: A direct comparison of the longitudinal reproducibility of 3D FID-CRT-MRSI across 3T and 7T has not been performed.

Goal(s): The aim was to determine the consistency of MRSI across these two field strengths in different brain regions.

Approach: The same subjects were scanned twice within a week at both fields and intra-subject and inter-subject Coefficients of Variation (CV%) for three metabolite ratios in different brain regions were calculated.

Results: The study found high reproducibility (CVs for most ROIs <10%) for both fields. 3T can provide sufficiently reproducible results by using larger voxel sizes and shorter measurement times.

Impact: The results will impact researchers and clinicians using MRSI, providing them with a reproducible technique at a clinical field strength of 3Tand7T and can be a method for those focusing on larger brain regions or longitudinal monitoring of metabolite changes.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.