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Abstract #1865

Super-resolution Y-Net for simultaneous 1H MRF/23Na MRI

Gonzalo Gabriel Rodriguez1,2, Hector Lise de Moura2, Ilias Giannakopoulos2, Riccardo Lattanzi2,3,4, Ravinder Regatte2,3, and Guillaume Madelin2,3
1NMR Signal Enhancement, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany, 2Bernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University School of Medicine, New York, NY, United States, 3Vilcek Institute of Graduate Biomedical Sciences, New York University School of Medicine, New York, NY, United States, 4Center for Advanced Imaging Innovation and Research, New York University School of Medicine, New York, NY, United States

Synopsis

Keywords: Non-Proton, Non-Proton, Super-resolution, fingerprinting

Motivation: To improve resolution for translating sodium MRI into clinical practice.

Goal(s): Develop a super-resolution neural network for brain sodium images.

Approach: A cascaded Y-Net is proposed to generate high-resolution sodium images from simultaneously acquired 1H MRF/23Na MRI data. Human brain images from 8 healthy subjects were used for training and validation (154), and testing (22).

Results: The generated high-resolution sodium images from the Y-Net showed a structural similarity index measure (SSIM) of 0.935, a RMSE=0.034 and a PSNR=28.8 compared with the ground truth.

Impact: We introduce a Y-Net super-resolution neural network that generates high-resolution sodium images from simultaneously acquired 1H MRF/23Na MRI data.

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Keywords