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Abstract #1902

Spatiotemporally Encoded Single-Sided MRI with a Numerical Point-Spread Function Reconstruction

Meredith Sadinski1, Muller De Matos Gomes1, Aleksander Nacev1, and William Grissom2
1Promaxo, Oakland, CA, United States, 2Case Western Reserve University, Cleveland, OH, United States

Synopsis

Keywords: Image Reconstruction, Prostate

Motivation: Motivation: Single-sided MRI scanners offer excellent interventional access but require novel approaches to image acquisition.

Goal(s): To generate distortion-free spatiotemporally encoded images with a single-sided low-field MRI scanner and validate the acquisitions in vivo.

Approach: Spatiotemporally encoded images were collected in phantom and volunteer and reconstructed using a numerical PSF-based reconstruction.

Results: Images of male and female subjects showed anatomic structures. Reconstruction with a numerical modeled PSF increased visibility of these structures and improved signal across the field of view in both phantom and human images relative to using a sinc-based PSF.

Impact: This methodology can be used for translation of an xSPEN encoded sequence into clinical practice and aid other researchers facing similar reconstruction challenges.

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Keywords