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Abstract #1912

Quantitively Accurate Bipolar Quantitative Chemical Shift Encoded Imaging Using the Gradient Impulse Response Function

James Hao Wang1,2, Diego Hernando1,2, Ali Pirasteh1,2, and Alan McMillan1,2
1Medical Physics, UW Madison, Madison, WI, United States, 2Radiology, UW Madison, Madison, WI, United States

Synopsis

Keywords: Image Reconstruction, Quantitative Imaging, GIRF, PDFF, CSE

Motivation: Quantitative chemical shift encoded (CSE) imaging enables accurate measurement of proton density fat fraction (PDFF) but requires breath holding that can be affected by motion artifacts.

Goal(s): We aim to develop a more rapid, bipolar readout CSE acquisition.

Approach: Gradient impulse response function (GIRF) was used to account for gradient-related phase errors that complicate PDFF measurements in bipolar acquisitions.

Results: Bipolar CSE with GIRF correction enabled accurate PDFF measurement with similar results to conventional unipolar readout CSE with a 40% reduction in scan time.

Impact: This study explores the application of GIRF and how it could be used in a bipolar CSE for PDFF measurement. Results are comparable to conventional unipolar CSE but yield significant scan time reduction.

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Keywords