Keywords: Image Reconstruction, Spectroscopy, multi-channel signal combination
Motivation: Multi-channel 31P MRSI signal combination is challenging due to low intrinsic SNR.
Goal(s): Improve multi-channel 31P signal combination for a multi-tuned 31P/23Na head coil receiver array.
Approach: Combining 15-channel 31P data using the 23Na sensitivity maps received with the same dual-tuned array. The results are evaluated quantitatively and qualitatively in silico, on phantom scans, and in vivo.
Results: Simulation shows <5% SNR-decrease by combining 31P signals using 23Na sensitivities. Phantom data shows 25% SNR-decrease but also potential for mitigating point-spreading effect. In vivo data analysis shows 5% SNR increase when the intrinsic SNR is low but 15% decrease after the dataset is denoised.
Impact: This study explores an alternative approach for multi-channel 31P MRSI signal combination. The performance is positive when intrinsic SNR is low. This approach can be extended to other X-nuclei with not-too-far Larmor frequencies if multi-tuned receiver antennas are used.
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