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Abstract #1934

CSF Flow Dynamics and Volume Changes in Sigmoid Sinus Wall Dehiscence-Pulsatile Tinnitus with Idiopathic Intracranial Hypertension

Lanyue Chen1, Xiaobo Ma1, Xiaoxia Qu1, Dandan Zheng2, Mengdi Zhou1, Xiwen Wang1, and Zhaohui Liu1
1Beijing Tongren Hospital, Beijing, China, 2Clinical & Technical Support, Philips Healthcare, Beijing, China

Synopsis

Keywords: Head & Neck/ENT, Fat, Pulsatile tinnitus. Sigmoid sinus dehiscence. Intracranial hypertension. Cerebrospinal fluid dynamics. Cerebrospinal fluid volume.

Motivation: The mechanism of sigmoid sinus dehiscence (SSWD) in pulsatile tinnitus (PT) patients remains unclear.

Goal(s): To assess the cerebrospinal fluid (CSF) dynamics and volume of SSWD-PT with intracranial hypertension by phase-contrast magnetic resonance imaging (PC-MRI).

Approach: Thirty-five PT patients with SSWD and intracranial hypertension identified on dual-phase contrast-enhanced CT (DP-CECT) and brain magnetic resonance venogram (MRV), respectively. And 35 age-, gender-, and handiness-matched healthy volunteers. All participants underwent T1-weighted volumetric and PC-MRI.

Results: The body mass index, regurgitant fraction and CSF volume were significantly higher and the mean velocity, peak velocity and mean flux were significantly slower in SSWD-PT.

Impact: We found the CSF dynamics and volume changes in SSWD-PT with intracranial hypertension, which may be related to blood flow dynamics changes in sigmoid sinus and presence of PT. These results suggest treatment for SSWD-PT should be more comprehensive.

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Keywords