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Abstract #1970

Compressed sense acquisition with artificial intelligence based denoising: evaluation in ultra-high field high resolution resting-state fMRI

Sheeba Anteraper1, Ivan E Dimitrov1,2, Johannes M Peeters3, Tom Geraedts3, Wim Prins3, and Anke Henning1
1Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, TX, United States, 2Philips Healthcare, Cambridge, MA, United States, 3Philips Healthcare, Best, Netherlands

Synopsis

Keywords: AI/ML Image Reconstruction, Brain Connectivity, Analysis/Processing, AI/ML Image Reconstruction

Motivation: Compressed Sense (CS) acquisition in combination with novel deep learning-based reconstructions has been shown as a viable acceleration technique that brings about additional artificial intelligence (AI) based denoising.

Goal(s): Here, we investigate the impact of CS-AI acceleration and denoising on high-resolution resting-state (rs)-fMRI analysis.

Approach: CS was performed, and different reconstruction methods were compared: (i) conventional CS, (ii) CS with moderate SmartSpeed AI based denoising and (iii) CS with strong SmartSpeed AI based denoising.

Results: Our preliminary results indicate that the underlying reconstruction CS nets do not introduce “artificial” noise or bias and are capable of generating the expected neuronal networks.

Impact: Increasing the rs-fMRI resolution, without sacrificing fidelity in functional connectivity maps, via the application of CS-AI, will lead to higher confidence in human brain mapping, thus reducing the number of participants needed to detect differences between healthy and clinical populations.

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Keywords