Keywords: Arterial Spin Labelling, Arterial spin labelling
Motivation: Velocity selective (VS)-ASL can be of great added benefit for fMRI at ultra-high field because of its specificity and ATT-insensitivity.
Goal(s): Our goal was to show the feasibility of VS-ASL at 7T with minimal TR, which involves minimizing SAR and timing parameters within the sequence.
Approach: VS-ASL was implemented using BIR4 labeling module and compared to the robust FAIR ASL. Image quality was measured based on quantified ASL-signal and tSNR-efficiency.
Results: Good agreement between FAIR and VSSinv-ASL was found. VSSinv-ASL was used to create intrinsic BGS without additional SAR. A shortest TR of 4500ms was achieved which could potentially be shorted with pTx.
Impact: We showed the feasibility of Velocity Selective (VS)-ASL at UHF and the application in fMRI. VS-ASL showed comparable but less homogeneous tSNR as FAIR. VS-ASL is of added benefit for fMRI at ultra-high field because of its specificity and ATT-insensitivity.
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