Keywords: Structural Connectivity, High-Field MRI, sleep
Motivation: The habenula is evolutionarily conserved brain region which play a crucial role in sleep regulation
Goal(s): To analysis the structural and functional relationship between habenula and individual sleep by 5T ultrahigh-resolution MRI
Approach: Using ultrahigh-resolution structural and functional MRI, we parcellated lateral and medial portions of the habenula and calculated structural and functional connectivity on the basis of these parcellations
Results: We parcellated lateral and medial portions of the habenula and identified connectivity with salience, limbic and part of somatomotor networks, which led to the loss in average sleep and cognitive processes
Impact: For the first time we identified the correlation between habenula and individual sleep using 5T ultrahigh-resolution MRI. By analyzing 300 samples high -resolution data, we revealed the neurological basis of individual sleep regulation, and provided new opinions for the mechanism of sleep diseases.
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