Keywords: White Matter, Kidney, hemodialysis
Motivation: The relationship between white matter hyperintensity (WMH) and altered cerebral blood flow (CBF) in maintenance hemodialysis patients remains unclear.
Goal(s): The study aims to explore the regulation of changes for CBF and its relationship with WMH burden in hemodialysis patients.
Approach: Hemodialysis patients were divided into two groups based on whether their CBF decreased after 3-year therapy. The severity of white matter hyperintensity was compared between the two groups.
Results: Compared with the increased CBF group, higher burden of deep WMH was found in the decreased CBF group.
Impact: This association between WMH and decrased CBF in maintenance hemodialysis be beneficial to the exploration of the complex mechanisms underlying the development of cerebral abnormalities during hemodialysis.
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