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Abstract #2093

Contrastive Learning with Multi-Contrast Constraints for Segmentation in Renal Magnetic Resonance Imaging

Aya Ghoul1, Lavanya Umapathy2, Cecilia Zhang3, Petros Martirosian3, Ferdinand Seith3, Sergios Gatidis1,4, and Thomas Küstner1
1Medical Image And Data Analysis (MIDAS.lab), Department of Diagnostic and Interventional Radiology, University Hospital of Tuebingen, Tuebingen, Germany, 2Department of Radiology, Center for Advanced Imaging Innovation and Research (CAI2R), New York University Grossman School of Medicine, New York, NY, United States, 3Department of Diagnostic and Interventional Radiology, University Hospital of Tuebingen, Tuebingen, Germany, 4Department of Radiology, Stanford University, Stanford, CA, United States

Synopsis

Keywords: Analysis/Processing, Segmentation, Reproducibility challenge, multi-parametric renal MRI, AI/ML Image segmentation, Kidney

Motivation: Supervised deep learning provides state-of-the-art medical image segmentation when large labeled images are accessible. However, manual segmentation suffers from prolonged delineation.

Goal(s): In response to the 2024 ISMRM Challenge “Repeat it With Me: Reproducibility Team Challenge”, we aim to show the effectiveness of contrastive learning to find suitable initialization for segmentation with limited annotation.

Approach: We use a multi-contrast contrastive loss guided by representational constraints to learn discriminating features within multi-parametric renal MR images and fine-tune the pretrained model on segmentation tasks.

Results: Our findings validate that pretraining diminishes the needed annotation effort by 60% for different imaging sequences and enhances segmentation performance.

Impact: Multi-contrast contrastive learning reduces annotation effort to train deep-learning segmentation models, confirming prior findings in a new cohort, within the 2024 ISMRM Challenge “Repeat it With Me: Reproducibility Team Challenge” and indicating its potential to improve multi-parametric imaging workflows.

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Keywords