Keywords: Diffusion Analysis & Visualization, High-Field MRI, diffusion-relaxation correlation spectroscopic imaging，brain
Motivation: Motivated by the promise of higher SNR and gradient performance at ultra-high magnetic fields (5T), we conducted in-vivo experiments of diffusion-relaxation correlation spectroscopic imaging (DR-CSI) to tap into its prospects at 5T.
Goal(s): This study aims to assess the feasibility and performance of DR-CSI at 5T for brain tissue measurement and to explore its 5T applications compared to 3T.
Approach: We have acquired two-dimensional diffusion-relaxation data and resolved the 2D spectra and spatial maps at both field strengths for comparative analysis.
Results: Results at 5T showed clearer differentiation of brain tissues and improved sensitivity to deep brain nuclei.
Impact: At 5T, diffusion-relaxation correlation spectroscopic imaging excels in estimating deep brain nuclei, promising for future applications in infarcts and neurodegenerative conditions.
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