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Abstract #2164

Superficial White Matter Classification using Diffusion MRI Tractography with Spiking Neural Networks

Aamir Sattar1,2, Cheng Li1, Fan Zhang3,4, Jianzhong He5, Hairong Zheng1, and Shanshan Wang1,6
1Paul C. Lauterbur Research Center for Biomedical Imaging, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China, 2University of Chinese Academy of Sciences, Beijing, China, 3University of Electronic Science and Technology of China, Chengdu, China, 4Harvard Medical School, Boston, MA, United States, 5Zhejiang University of Technology, Hangzhou, China, 6Peng Cheng Laboratory, Shenzhen, China

Synopsis

Keywords: Tractography, Brain, Diffusion MRI, Spiking Neural Network, Superficial White Matter Classification, Tractography

Motivation: The investigation of superficial white matter (SWM) poses challenges due to its small size, variability, delicate structure, high curvature, and fiber crossings in diffusion MRI tractography.

Goal(s): Our goal is to develop an innovative methodology for classifying SWM streamline clusters using diffusion MRI tractography, leveraging brain-inspired learning-based techniques.

Approach: A dual-phase method with Spiking Neural Networks (SNNs) and leaky integrate and fire (LIF) neurons is developed for the classification of 199 SWM clusters.

Results: Experiments were conducted using two open-source datasets, and our method achieves accurate SWM classification results with an accuracy of 93.73%.

Impact: The findings of this study on SWM classification hold great potential for facilitating analyses of SWM within neuroscientific research, contributing to understanding the complexities and alterations in SWM associated with various health conditions and neurological disorders.

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