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Abstract #2177

Ultrafast simultaneous T2 and T2* mapping in 150 ms using non-Cartesian single-shot SPEN MRI

Junxian Jin1, Lin Chen1, and Zhong Chen1
1Department of Electronic Science, Fujian Provincial Key Laboratory of Plasma and Magnetic Resonance, School of Electronic Science and Engineering, National Model Microelectronics College, Xiamen University, Xiamen, China

Synopsis

Keywords: Relaxometry, Relaxometry, T2 Mapping, T2* Mapping

Motivation: T2 and T2* mapping can quantitatively characterize tissue pathologies, improving diagnosis and treatment, but their clinical applications are hindered by relatively long scan times.

Goal(s): To develop an ultrafast method for simultaneously obtaining T2 and T2* mapping.

Approach: A biaxial spatiotemporally encoded (SPEN) sequence with multi-spin-echo trains and spiral out-in-out-in trajectory was developed to obtain multiple images with different echo times within a single shot. The acquired signal was fitted to yield simultaneous T2 and T2* mapping.

Results: Numerical simulations and in vivo rat brain and kidney experiments were conducted to validate the proposed method.

Impact: We developed an ultrafast technique to simultaneously obtain T2 and T2* mapping in 150 ms, potentially facilitating the use of T2 and T2* mapping in scenarios requiring high time resolution.

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