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Abstract #2250

In Vivo Reproducibility of T2 and T1rho Relaxation Times in Multiple Coils and Sequences

Yael Vainberg1, Anthony Gatti1, Anoosha Pai S.1, and Feliks Kogan1
1Radiology, Stanford University, Stanford, CA, United States

Synopsis

Keywords: Osteoarthritis, Cartilage, Reproducibility, coils

Motivation: T2 and T1rho reproducibility is essential for evaluating the small changes that occur during early osteoarthritis that are predictive of disease progression.

Goal(s): To evaluate the reproducibility of T2 and T1rho relaxation times in multiple coils and with multiple imaging sequences.

Approach: We studied the reproducibility of T1rho and T2 relaxation times with a MAPSS and qDESS sequence in a Transmit-Receive knee coil and two different flexible extremity coil arrays.

Results: Intra-coil CVs of less than 5% (QIBA Goal) in qDESS T2 measurements with all coils tested, MAPSS T2 measurements with both flexible-coil-arrays and MAPSS T1rho measurements only with the Air coil.

Impact: Preliminary findings suggest that flexible, receive-only coil arrays show similar or improved reproducibility for evaluating cartilage T2 and T1rho relaxation times compared to standard T/R knee coils.

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