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Abstract #2256

Repeatability of Quantitative T1, T2 and T Mapping of Knee Cartilage with 3D-MR Fingerprinting

Xiaoxia Zhang1,2, Hector L.de Moura1,2, Anmol Monga1,2, Marcelo V.W. Zibetti1,2, Richard Kijowski1,2, and Ravinder R. Regatte1,2
1Bernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University Grossman School of Medicine, New York, NY, United States, 2Center for Advanced Imaging Innovation and Research (CAI2R), Department of Radiology, New York University Grossman School of Medicine, New York, NY, United States

Synopsis

Keywords: Cartilage, Cartilage

Motivation: 3D-MRF sequence for simultaneous multi-parametric mapping has the potential to provide a more time-efficient comprehensive evaluation of the knee cartilage.

Goal(s): However, evaluation of 3D-MRF repeatability of knee cartilage is limited.

Approach: 3D-MRF and conventional sequences for knee cartilage were acquired four times on fourteen healthy subjects. Multi-parametric maps were computed and repeatability was evaluated.

Results: High inter- and intra-subject repeatabilities were found using the 3D-MRF sequence over seven days with good agreement to conventional sequences.

Impact: The 3D-MRF sequence showed high T1, T2, and T repeatability on knee cartilage on different days and good agreement with conventional methods.

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Keywords