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Abstract #2260

ROI based Multi-parameter Quantitative Network(RMQ-Net) with Uncertainty-awareness for Quantitative UTE MRI Study of Cartilage

Xing Lu1, Kevin Du1, Yajun Ma1, Jiyo Athertya1, Bhavsimran Singh Malhi1, Eric Y Chang1,2, Susan V Bukata1,3, and Christine Chung1,2
1Department of Radiology, University of California, San Diego, San Diego, CA, United States, 2Radiology Service, Veterans Affairs San Diego Healthcare System, San Diego, CA, United States, 3Department of Orthopaedic Surgery, University of California San Diego, San Diego, CA, United States

Synopsis

Keywords: Cartilage, MSK

Motivation: Quantitative MRI (qMRI) studies of cartilage regions need both regional segmentation and pixel-wise fitting analysis, which can be time-consuming and subject to inter-individual variability.

Goal(s): To design a deep neural network for simultaneous qMRI mapping and accurate tissue segmentation.

Approach: By leveraging different scan sequences, we proposed a RMQ-net with Uncertainty-awareness(UA) module, or UA-QMR-net. A majority-voting strategy was applied for robust cartilage segmentation and accelerated qMRI analysis.

Results: The results demonstrated that the UA-RMQ-net achieved higher performance than the original RMQ-net for both UTE-T1 and UTE-T1r analyses of articular cartilage.

Impact: By leveraging information from different scan sequences, the proposed UA-RMQ-net could obtain higher performance for accelerated qMRI analysis.

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