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Abstract #2266

Fully Automated Whole-Leg multiparametric quantitative MRI processing, segmentation and analysis.

Martijn Froeling1, Lara Schlaffke2, and Linda Heskamp1
1Department of Radiology, UMC Utrecht, Utrecht, Netherlands, 2Department of Neurology, BG-University Hospital Bergmannsheil gGmbH, Bochum, Germany

Synopsis

Keywords: Muscle, Quantitative Imaging, Analysis/Processing; Software Tools

Motivation: Quantitative magnetic resonance imaging (qMRI) is a common tool for assessing neuromuscular disorders, but its quantitative parameters often lack specificity and generally do not directly relate to muscle function.

Goal(s): In our ongoing MOTION study, we are collecting whole-leg qMRI data and assessing muscle structure, function, and lifestyle in a large cross-sectional cohort to identify confounding factors in qMRI evaluation.

Approach: To streamline data analysis for this cohort, we've developed a fully automated muscle-Bids-based data analysis pipeline, including automated muscle segmentation.

Results: Here, we introduce our data analysis pipeline, demonstrated using repeated scans of one volunteer.

Impact: The implementation of fully automated qMRI data processing streamlines large-scale studies and enhances its integration into clinical workflows. This standardization we expect to reduces variability for more dependable and reproducible outcomes.

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Keywords