Abstract #2337

Correction of breathing-induced dynamic field changes in the cervical cord using FID navigators at 3T

Anna Lebret¹, Mustafa Utkur^2,3, Tess E Wallace⁴, Tobias Kober^5,6,7, Onur Afacan^2,3, and Maryam Seif^1,8

¹Spinal Cord Injury Center, Balgrist University Hospital, Zurich, Switzerland, ²Radiology, Harvard Medical School, Boston, MA, United States, ³Computational Radiology Laboratory, Boston Children's Hospital, Boston, MA, United States, ⁴Siemens Medical Solutions USA Inc., Boston, MA, United States, ⁵Advanced Clinical Imaging Technology Group, Siemens Healthcare International AG, Lausanne, Switzerland, ⁶Radiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland, ⁷LTS5, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland, ⁸Department of Neurophysics, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany

Synopsis

Keywords: Spinal Cord, Spinal Cord

Motivation: To correct breathing-induced field fluctuations and ensuing artifacts on T2*-weighted MRI of the cervical cord to improve T2* mapping.

Goal(s): To characterize B₀ field changes caused by respiration within the cervical cord and to retrospectively compensate for those spatiotemporal fluctuations using a FID navigator-based correction technique.

Approach: B₀ field coefficients up to second order were measured using FID navigators and a multi-channel low-resolution reference image. Retrospective correction was performed using measured field coefficients during an iterative image reconstruction.

Results: The FIDnav framework characterized the B₀ field changes and improved the quality of T2*-weighted MRI and T2* maps by correcting respiratory-induced artifacts.

Impact: Improved quality of T2*-weighted images, obtained after correction of respiration-induced field changes, holds promise for improving MRI techniques relying on T2* contrast (BOLD fMRI, QSM) and clinical applications in neurological diseases of the cervical cord.

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