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Abstract #2439

3D Diffusion Image Acquisition with Motion Offsetting and

Navigation-Dependent Segmentation (DIAMONDS)

Jens Johansson1,2, Kerstin Lagerstrand2,3, Hanna Hebelka1,4, and Stephan E. Maier1,5
1Radiology, Clinical Scienes, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden, 2Medical Physics and Biomedical Engineering, Sahlgrenska University Hospital, Gothenburg, Sweden, 3Medical Radiation Sciences, Clinical Scienes, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden, 4Radiology, Sahlgrenska University Hospital, Gothenburg, Sweden, 5Radiology, Brigham and Women's Hospital, Boston, MA, United States

Synopsis

Keywords: Diffusion Acquisition, Diffusion/other diffusion imaging techniques, 3D-DWI; Motion-compensated diffusion imaging; Diffusion acquisition

Motivation: Investigate whether 1D navigator echo phase information can be used to correct residual phase errors in single thick-slab segmented 3D-DWI with first and second order motion-compensated diffusion encoding gradients.

Goal(s): Perform high-resolution single thick-slab segmented 3D-DWI with full brain coverage.

Approach: Extend a first and second order motion-compensated segmented 3D-DWI sequence with three orthogonal 1D navigators, which are utilized to correct for residual phase errors.

Results: Correction of zeroth order phase shifts, which result from translation, demonstrated reduction of ghosting artifacts. First order phase terms, which arise from rotation, were also determined, but require a more complex correction strategy.

Impact: Motion-compensated single thick-slab segmented 3D-DWI with orthogonal 1D navigators is a completely novel and promising approach for high resolution diffusion imaging with full brain coverage.

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Keywords