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Abstract #2440

Spiral interleaving for diffusion encoding and relaxometry (SPIDER)

Xingwang Yong1,2,3, Hong-Hsi Lee2, Shohei Fujita2,3,4,5, Yohan Jun2,3, Jaejin Cho2,3, Qiang Liu6, Tao Zu1, Yi Zhang1, and Berkin Bilgic2,3,7
1Key Laboratory for Biomedical Engineering of Ministry of Education, Department of Biomedical Engineering, College of Biomedical Engineering & Instrument Science, Zhejiang University, Hangzhou, China, 2Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States, 3Department of Radiology, Harvard Medical School, Boston, MA, United States, 4Department of Radiology, Juntendo University, Tokyo, Japan, 5Department of Radiology, The University of Tokyo, Tokyo, Japan, 6Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States, 7Harvard/MIT Health Sciences and Technology, Cambridge, MA, United States

Synopsis

Keywords: Diffusion Acquisition, Diffusion Tensor Imaging

Motivation: Current diffusion readout methods have a relatively long echo time and readout duration, which prevent multi-echo imaging.

Goal(s): To implement a diffusion sequence with multiple echoes readout for performing diffusion relaxometry.

Approach: A 3-echo diffusion sequence, SPIDER, with variable density spiral readout was designed.

Results: The proposed SPIDER showed comparable images with reference EPI method at shorter echo time.

Impact: The proposed method showed the ability to acquire 3 echoes for 1mm2 resolution for low b-value, which could help multi-echo diffusion modeling.

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Keywords