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Abstract #2453

QSM Reconstruction of Arbitrary Dipole Orientations using an End-to-end Neural Network via Latent Feature Editing

Yang Gao1, Zhuang Xiong2, Shanshan Shan3, Min Li1, Alan H Wilman4, G. Bruce Pike5, Feng Liu2, and Hongfu Sun2
1School of Computer Science and Engineering, Central South University, Changsha, China, 2School of EECS, The University of Queensland, Brisbane, Australia, 3State Key Laboratory of Radiation, Medicine and Protection, Soochow University, Suzhou, China, 4University of Alberta, Edmonton, AB, Canada, 5University of Calgary, Calgary, AB, Canada

Synopsis

Keywords: Susceptibility/QSM, Quantitative Susceptibility mapping, Orientation-Adaptive, Latent Feature Editing, OA-iQSM

Motivation: The performances of most DL-QSM methods are limited to MRI phase data of pure-axial acquisition orientation.

Goal(s): In this work, we would like to propose a novel DL-based end-to-end neural network for QSM reconstruction from phase data of arbitrary dipole orientations.

Approach: A novel Latent Feature Editing (LFE) module to learn the encoding of acquisition orientation vectors and seamlessly integrate them into the latent features of deep networks to make them orientation-adaptive.

Results: Both simulated and in vivo experiments demonstrate that the proposed LFE module can result in desirable QSM images at arbitrary oblique head orientations.

Impact: This work introduces a new DL paradigm, allowing researchers to develop innovative QSM methods without requiring a complete overhaul of their existing architectures.

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Keywords