Abstract #2481

Echo-uT1RESS Sequence with Radial Stack-of-Stars Acquisition for Dynamic Contrast-Enhanced Dark Blood Imaging

Ruoxun Zi^1,2,3, Robert R Edelman⁴, Christoph Maier^1,2, Mahesh Bharath Keerthivasan⁵, Riccardo Lattanzi^1,2, and Kai Tobias Block^1,2

¹The Bernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University Grossman School of Medicine, New York, NY, United States, ²Center for Advanced Imaging Innovation and Research (CAI2R), Department of Radiology, New York University Grossman School of Medicine, New York, NY, United States, ³Vilcek Institute of Graduate Biomedical Sciences, New York University Grossman School of Medicine, New York, NY, United States, ⁴Radiology, Northshore University HealthSystem, Evanston, IL, United States, ⁵Siemens Medical Solutions, New York, NY, United States

Synopsis

Keywords: Blood Vessels, Tumor, dark-blood DCE

Motivation: Scans with dark-blood contrast can improve the conspicuity of small metastases in contrast-enhanced brain examinations and may be useful for vessel-wall imaging.

Goal(s): To describe a novel sequence, called echo-uT1RESS, that overcomes the limitations of the frequently utilized T1 SPACE sequence.

Approach: The proposed stack-of-stars echo-uT1RESS sequence applies saturation-recovery preparation followed by 3D PSIF readout. Due to radial k-space acquisition, scans are motion-insensitive and can be acquired during free breathing. Dynamic contrast-enhanced images can be obtained through GRASP reconstruction.

Results: Evaluation in a small patient cohort demonstrated high conspicuity of enhancing lesions and vessel walls with reduced motion artifacts compared to conventional sequences.

Impact: The described radial echo-uT1RESS sequence offers improved lesion-to-background and dark-blood contrast. The sequence may help to increase the sensitivity for detecting small metastases and may find application in vessel-wall imaging. It is also compatible with dynamic imaging using GRASP reconstruction.

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