Abstract #2488

Evaluation of Acceleration Methods for Clinical T1-weighted (T1w) Vessel Wall Imaging

Shraddha Pandey¹, Manuel Taso², Zhaoyang Fan³, Konstanze Guggenberger⁴, Alexia Tran⁵, Scott Raymond⁶, Shawn Lyo¹, Marisa Sanchez¹, Rob Sellers², Julien Savatovsky⁵, Chengcheng Zhu⁷, Jae Song¹, and M. Dylan Tisdall¹

¹Department of Radiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, United States, ²Siemens Medical Solutions USA Inc, Malvern, PA, United States, ³Department of Radiology, Keck School of Medicine of USC, Los Angeles, CA, United States, ⁴Department of Radiology, University Hospital of Würzburg, Würzburg, Germany, ⁵Hôpital Fondation Adolphe de Rothschild, Paris, France, Metropolitan, ⁶Department of Radiology, The University of Vermont Medical Center, Burlington, VT, Canada, ⁷Department of Radiology, University of Washington, Medical Center, Seattle, WA, United States

Synopsis

Keywords: Blood Vessels, Blood vessels, Vessel Wall Imaging, Accelerated Acquisition, Compressed Sensing

Motivation: Clinical VWI scans demand high spatial resolutions, which lead to extended acquisition times, potentially causing limited field-of-view (FOV), motion artifacts, and patient burden.

Goal(s): We evaluated FDA-approved acceleration methods for 3D T1w SPACE to develop optimized protocols for clinical VWI studies.

Approach: Compressed Sensing (CS) and CAIPI acceleration techniques optimized to reduce scan times and provide whole-head coverage were compared against our current GRAPPA accelerated limited-FOV clinical protocol.

Results: The whole-head FOV combined with CS yielded image quality comparable to our current clinical protocol but with almost half the scan time, promising significant reductions in lengthy clinical VWI protocols and patient burden.

Impact: Compressed Sensing enabled increased FOV imaging with substantially reduced scan times without significant loss of image quality compared to CAIPI and standard-of-care GRAPPA-accelerated techniques for a clinical T1-weighted vessel wall imaging protocol.

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