Abstract #2529

Influence of Maternal Position on Fetal Organ Oxygenation using Low Field MR

Kelly Payette^1,2, Jordina Aviles Verdera^1,2, Alena U. Uus^1,2, Joseph V. Hajnal^1,2, Lisa Story^1,2,3, Megan Hall^1,2,3, Mary A. Rutherford¹, and Jana Hutter^1,2,4

¹Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom, ²Biomedical Engineering Department, School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom, ³Department of Women and Children’s Health, St Thomas’ Hospital, King's College London, London, United Kingdom, ⁴Smart Imaging Lab, Radiological Institute, University Hospital Erlangen, Erlangen, Germany

Synopsis

Keywords: Fetal, Fetus

Motivation: Maternal supine sleeping position in the third trimester has been linked to decreased uterine blood flow and increases in stillbirth.

Goal(s): To investigate the impact of maternal position on fetal and placental T2* values by taking advantage of the increased dynamic T2* range at low field strengths

Approach: We acquired dynamic whole uterus multi-echo gradient echo sequences at 0.55T with the subject in both left lateral and supine positions and compare the T2* placental and fetal body organ values organs in 91 subjects.

Results: Significant differences in mean T2* values were observed between both positions in the placenta and 7 fetal body organs.

Impact: Maternal position significantly impacts mean placental and fetal body T2* values. In addition, future quantitative fetal T2* studies should consider maternal position in their study design.

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