Abstract #2561

Comparison of single-shot, FOCUS single-shot, MUSE, and FOCUS MUSE diffusion weighted imaging for pulmonary lesions: a pilot study

Li Fan¹, Jie Li^1,2, Yi Xia¹, Jiankun Dai³, Guangyuan Sun⁴, Meiling Xu¹, Xiaoqing Lin^1,2, Lingling Gu¹, Jie Shi³, and Shiyuan Liu¹

¹Department of Radiology, Second Affiliated Hospital of Naval Medical University, Shanghai, China, ²College of Health Sciences and Engineering, University of Shanghai for Science and Technology, Shanghai, China, ³MR Research，GE Healthcare, Beijing, China, ⁴Department of Thoracic Surgery, Second Affiliated Hospital of Naval Medical University, Shanghai, China

Synopsis

Keywords: DWI/DTI/DKI, Diffusion/other diffusion imaging techniques, Magnetic resonance imaging; Diffusion weighted imaging; Lung; Pulmonary lesions

Motivation: DWI has been used for pulmonary lesion assessment. But clinical single-shot (SS) EPI DWI for lung is prone to susceptibility distortions. FOCUS SS, MUSE, and FOCUS MUSE are improved EPI-based techniques which are less sensitive to susceptibility artifacts. However, their performance for lung DWI remains unknown.

Goal(s): Performance comparison among the four sequences for lung DWI.

Approach: 44 patients were recruited, and each was imaged with the four sequences. Image quality and diagnostic performance of benign and malignant lesion discrimination were compared.

Results: FOCUS MUSE had least distortions and best diagnostic performance.

Impact: Application of FOCUS MUSE would be beneficial for lung lesion assessment.

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