Abstract #2562

Comparative study of time-dependent diffusion MRI and conventional DWI for microstructural characterization of breast lesions

Xue Li¹, Jie Lu², Lei Jiang¹, Chunmei Li¹, Haotian Li², Kuiyuan Liu², Yanglei Wu³, Dan Wu², and Min Chen¹

¹Department of Radiology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, China, ²Key Laboratory for Biomedical Engineering of Ministry of Education, Department of Biomedical Engineering, College of Biomedical Engineering & Instrument Science, Zhejiang University, Zhejiang, China, ³MR Research Collaboration, Siemens Healthineers, Beijing, China

Synopsis

Keywords: Microstructure, Diffusion/other diffusion imaging techniques, apparent diffusion coefficient; MRI; breast lesions

Motivation: Time-dependent diffusion MRI (dMRI), thanks to its distinct advantages in characterizing tissue microstructure, has gained increasing popularity in clinical research in recent years.

Goal(s): However, its potential for distinguishing breast lesions remains uncertain.

Approach: The present study was conducted to compare the diagnostic performance of time-dependent dMRI parameters and ADC metrics derived from conventional DWI for breast lesions.

Results: The study results suggest that microstructural parameters based on time-dependent dMRI are superior to conventional DWI measurements in diagnosing breast lesions, and that the addition of time-dependent dMRI parameters improves the performance of conventional DWI in differentiating breast lesions.

Impact: Herein, the microstructural characteristics of breast lesions were investigated using time-dependent dMRI technique and compared with conventional DWI. It was found that that adding time-dependent dMRI parameters could improve the performance of conventional DWI in the diagnosis of breast cancer.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.