Keywords: Microstructure, Prostate
Motivation: VERDICT diffusion imaging and modelling for prostate cancer characterisation requires significant scan time which hinders its clinical practicality.
Goal(s): We aim to reduce the scan time requirement of VERDICT through paired model simplification and acquisition reduction whilst retaining model fitting accuracy and diagnostic performance.
Approach: We evaluated the model fitting accuracy and diagnostic performance of three simplified VERDICT schemes on 97 patients who underwent targeted biopsy.
Results: Our results demonstrate that a scan time reduction of ≈30% can be achieved with minimal impact to performance; model parameters were recovered with <5% mean bias and no significant change in diagnostic performance was observed.
Impact: Reducing the scan time of VERDICT diffusion imaging could help to enable integration of VERDICT into clinical practice which could help to reduce the number of healthy men referred for biopsy.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords