Keywords: Diffusion Modeling, Tumor
Motivation: Accurate grading of clear cell renal cell carcinoma (ccRCC) is essential for treatment decisions, particularly in patients with comorbidities.
Goal(s): This study aims to investigate time-dependent diffusion MRI to noninvasively characterize the microstructural properties of ccRCC and distinguish between different pathological grades.
Approach: A total of 66 patients with histologically confirmed ccRCC underwent MRI scans, and microstructural parameters were estimated using time-dependent diffusion MRI techniques.
Results: The study revealed distinct microstructural differences between low-grade and high-grade ccRCC, showing the potential of time-dependent diffusion MRI for preoperative pathological grade characterization.
Impact: This study has the potential to reshape the landscape of preoperative ccRCC grading, promote objectivity in treatment planning.
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