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Abstract #2583

Qualitative and quantitative assessment of accelerated liver DWI using deep learning reconstruction in oncologic patients

Mihaela Rata1,2, Francesca Castagnoli1,2, Joshua Shur1, Emily Evans1, Georgina Hopkinson1, Thomas Benkert3, Elisabeth Weiland3, Dow-Mu Koh1,2, and Jessica M Winfield1,2
1MRI Unit, Royal Marsden Hospital, Sutton, United Kingdom, 2Division of Radiotherapy and Imaging, The Institute of Cancer Research, London, United Kingdom, 3MR Application Predevelopment, Siemens Healthineers AG, Erlangen, Germany

Synopsis

Keywords: Diffusion Reconstruction, Liver, deep learning reconstructed Diffusion Weighted Imaging

Motivation: Deep learning (DL) reconstructions can improve image quality and/or reduce acquisition time in diffusion-weighted imaging (DWI).

Goal(s): This study aims to assess, quantitatively and qualitatively, DL-accelerated DWI in 50 patients with colorectal cancer undergoing liver examinations.

Approach: Three DWI series are compared: a moderately-accelerated DL-DWI, a corresponding standard reconstruction and a highly-accelerated DL-DWI.

Results: The moderately-accelerated DL reconstruction method provides better image quality than a standard reconstruction. Its ADC estimates in liver, spleen and liver metastases are slightly higher than ADC estimates from the standard reconstruction.

Impact: This study evaluated DL-accelerated DWI in 50 patients undergoing liver examinations by comparing three DWI series. The moderately-accelerated acquisition with DL reconstruction provided better image quality versus the standard reconstruction; its ADC was slightly higher than the standard-based ADC.

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Keywords