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Abstract #2586

Application of 5 diffusion models in bladder cancer staging based on the date of diffusion spectrum imaging

Chunmiao Xu1, Xiaoxian Zhang2, Xuejun Chen1, and Shaoyu Wang3
1Affiliated Cancer Hospital of Zhengzhou University; Henan Cancer Hospital, Zhengzhou, China, 2Radiology, Affiliated Cancer Hospital of Zhengzhou University; Henan Cancer Hospital, Zhengzhou, China, 3Siemens Healthcare, Shanghai ,China, Shanghai, China

Synopsis

Keywords: Diffusion Modeling, Diffusion/other diffusion imaging techniques

Motivation: The pathological grade of bladder cancer is closely related to the choice of treatment and the prognosis1. Diffusion spectrum imaging (DSI) is a newly developed model, which is helpful in distinguish benign and malignant tumors2.

Goal(s): This study was to explore the quantitative parameter from DSI in differentiating pathology grade of bladder cancer.

Approach: The differences of DSI quantitative parameter between high-grade and low-grade lesions and the differentiation performance of the indices were evaluated .

Results: Quantitative parameters of DSI could effectively distinguish pathology grade of bladder cancer, and AUC ranged from 0.790 to 0.960.

Impact: The quantitative parameters obtained from Diffusion spectrum imaging are more stable and can predict the pathological grade of bladder cancer better than traditional ADC.

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