Abstract #2613
Patterns of Popular Artifacts in QSM and χ-separation (chi-separation)
Hayeon Lee1, Kyeongseon Min1, Sooyeon Ji1, Jonghyo Youn1, Taechang Kim1, Jiye Kim1, Beomseok Sohn2, Woo Jung Kim3,4, Chae Jung Park5, Soohwa Song6, Dong Hoon Shin6, Kyung Won Chang7, Na-Young Shin8, Phil Hyu Lee9, Yangsean Choi10, Yoonho Nam11, Koung Mi Kang12, Agnieszka Burzynska13,14, Catherine Lebel15,16, and Jongho Lee1
1Department of Electrical and Computer Engineering, Seoul National University, Seoul, Korea, Republic of, 2Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea, Republic of, 3Institute of Behavioral Sciences in Medicine, Yonsei University College of Medicine, Seoul, Korea, Republic of, 4Department of Psychiatry, Yongin Severance Hospital, Yonsei University College of Medicine, Yongin, Korea, Republic of, 5Department of Radiology, Yongin Severance Hospital, Yonsei University College of Medicine, Yongin, Korea, Republic of, 6Heuron Co., Ltd, Seoul, Korea, Republic of, 7Department of Neurosurgery, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea, Republic of, 8Department of Radiology, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea, Republic of, 9Department of Neurology, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea, Republic of, 10Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Centre, Seoul, Korea, Republic of, 11Division of Biomedical Engineering, Hankuk University of Foreign Studies, Yongin, Korea, Republic of, 12Department of Radiology, Seoul National University Hospital, Seoul, Korea, Republic of, 13Department of Human Development and Family Studies, Colorado State University, Fort Collins, CO, United States, 14Department of Molecular, Cellular and Integrative Neurosciences, Colorado State University, Fort Collins, CO, United States, 15Alberta Children's Hospital Research Institute (ACHRI), Calgary, AB, Canada, 16Department of Pediatrics, University of Calgary, Calgary, AB, Canada
Synopsis
Keywords: Susceptibility/QSM, Artifacts, chi-separation
Motivation: In QSM and χ-separation (chi-separation), artifacts from various sources may be introduced. The oversight of these artifacts could lead researchers to analyse inaccurate maps, resulting in potentially erroneous conclusions.
Goal(s): The primary objective of this research is to investigate the characteristics, origins, and solutions related to artifacts encountered in QSM and χ-separation.
Approach: We processed QSM and χ-separation in 364 subjects from Parkinson’s disease, Alzheimer’s disease, hypertension, and alcohol-exposed adolescents development studies, reporting various types of artifacts. They are categorized and explored for origins and potential solutions.
Results: This study identified and provided solutions for 11 artifact types.
Impact: While processing QSM and χ-separation in diverse subjects and vendors, various artifacts emerged. This study categorized these artifacts, investigated origins, mitigation strategies, and discernible effects on QSM and χ-separation results, aiding researchers and practitioners in artifact identification, correction, and exclusion.
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