Abstract #2638

Feasibility Assessment of Measuring ADC of Meningeal Lymphatic Vessels using High-Resolution MUSE DWI and PROPELLER DWI

Chun-Han Liao^1,2,3, Yung-Yin Cheng^1,4, Shin-Lei Peng⁵, Hing-Chiu Chang⁶, Shao Chieh Lin^1,7, Chun-Jung Juan⁷, Chang-Hsien Liu⁷, Ya- Hui Lee⁷, Chao-Chun Lin⁸, Chia-Wei Lin⁸, and Yi-Jui Liu⁹

¹Ph.D. program in Electrical and Communication Engineering, Feng Chia University, Taichung, Taiwan, ²Department of Medical Imaging, Yuanlin Christian Hospital, Changhua, Taiwan, ³Department of Medical Imaging, Changhua Christian Hospital, Changhua, Taiwan, ⁴Department of Medical Imaging, Chung Shan Medical University Hospital, Taichung, Taiwan, ⁵Department of Biomedical Imaging and Radiological Science, China Medical University, Taichung, Taiwan, ⁶Department of Biomedical Engineering, The Chinese University of Hong Kong, Hong Kong, Hong Kong, ⁷Department of Medical Imaging, China Medical University Hsinchu Hospital, Hsinchu, Taiwan, ⁸Department of Radiology, China Medical University Hospital, Taichung, Taiwan, ⁹Department of Automatic Control Engineering, Feng Chia University, Taichung, Taiwan

Synopsis

Keywords: Vessels, Diffusion/other diffusion imaging techniques, MUSE, PROPELLER, Meningeal lymphatics vessels

Motivation: Is it possible to water diffusion be measured in meningeal lymphatic vessels (MLVs)?

Goal(s): Diffusion-weighted MRI is employed to assess the circulatory condition of MLVs, eliminating the need for MRI with contrast agent administration, which typically requires monitoring for over 4 hours.

Approach: Water diffusion measurements in MLVs were conducted using MUSE DWI and PROPELLER DWI, which offer low image distortion and high resolution.

Results: Our results indicate that MLVs were clearly visible on high spatial resolution DWI and ADC maps, and the ADC values of MLVs are higher than those of GM and WM but lower than CSF.

Impact: Since evaluating the circulatory condition of meningeal lymphatic vessels takes over 4 hours by contrast agent injection, our study investigates the feasibility of assessing the ADC of meningeal lymphatic vessels using high-resolution MUSE DWI and PROPELLER DWI.

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