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Abstract #2641

Reducing pulsation artifacts in 3D time-of-flight angiography at 7T using locally-scrambled ordering of the acquisition

Rita Schmidt1, Amir Seginer2, Dana Niry3,4, and Edna Furman-Haran2
1Department of Brain Sciences, Weizmann Institute of Science, Rehovot, Israel, 2Life Sciences Core Facilities, Weizmann Institute of Science, Rehovot, Israel, 3Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel, 4Department of Radiology, Tel Aviv Sourasky Medical Center, Tel-Aviv, Israel

Synopsis

Keywords: Artifacts, Velocity & Flow, acquisition order; angiography

Motivation: Non-contrast-enhanced time-of-flight (TOF) at 7T greatly improves the delineation of small vessels but is impaired by pulsation artifacts.

Goal(s): Our goal was to reduce pulsation artifacts in 3D TOF to better delineate vessels.

Approach: We recently developed “local-scrambling” which generates semi-random acquisition ordering to reduce artifacts from semi-periodic local signal fluctuations. This local-scrambling was tested in 3D TOF to reduce pulsatile blood flow artifacts in human scanning at 7T.

Results: Artifacts from pulsatile blood flow were significantly reduced using the new local-scrambling (of the 2D phase encodes), both for line-by-line and center-out acquisitions. The method can be of special interest for high-resolution angiography.

Impact: Increased resolution of non-contrast-enhanced time-of-flight (TOF) can provide more accurate vessels delineation. A new local-scrambling acquisition scheme can significantly improve 3D angiography by reducing interference noise and pulsation artifacts without requiring any changes to the reconstruction scheme.

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