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Abstract #2646

Mitigating Distortion Artifacts in Accelerated-EPI Using an Ensemble of k-t GRAPPA Kernels (EnKT-GRAPPA)

Yimeng Lin1, Daniel Raz Abraham2,3, Nan Wang2,3, and Kawin Setsompop2,3
1Center for Biomedical imaging Research, Tsinghua University, Beijing, China, 2Electrical Engineering, Stanford University, Stanford, CA, United States, 3Radiology, Stanford University, Stanford, CA, United States

Synopsis

Keywords: Artifacts, Artifacts

Motivation: EPI suffers from field-inhomogeneity distortions. Employing large inplane acceleration (Rinplane) can mitigate this issue at a cost of increase noise and artifacts, while postprocessing correction can lead to resolution-loss.

Goal(s): Develop a reconstruction method based on an ensemble of k-t GRAPPA-kernels (EnKT-GRAPPA) for use on moderately-accelerated EPI, to both fill missing-kspace and reduce distortion.

Approach: EnKT-GRAPPA kernels are trained using k-t calibration data to fill missing-kspace and correct for cumulative-phase of field-inhomogeneity in one step, where phase/distortion correction level can be flexibly tuned.

Results: For the same distortion mitigation level, EnKT-GRAPPA-reconstructed-images exhibit higher-SNR compared to those from conventional GRAPPA-reconstructed-images of a higher-Rinplane acquisition.

Impact: EnKT-GRAPPA enables moderately accelerated EPI to achieve a high level of distortion mitigation while preserving SNR. This method should be useful in many applications such as fMRI, diffusion and perfusion imaging.

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Keywords