Keywords: Low-Field MRI, Lung
Motivation: Parametric mapping may enable early detection and monitoring of pulmonary diseases but is hampered by low signal levels, short T2/T2* values, and susceptibility artifacts.
Goal(s): This project aims to develop an MRF approach for simultaneous 2D T1, T2, and M0 mapping in the lungs on a commercial 0.55T scanner.
Approach: MRF data were acquired in five healthy subjects during a 16s breathhold, repeated at end-inspiration and end-expiration, and reconstructed using a deep image prior.
Results: Feasibility of lung MRF at 0.55T was demonstrated in healthy subjects, with lung T1 of 868±57ms (expiration) and 806±59ms (inspiration), and T2 of 54.1±3.2ms (expiration) and 58.7±4.0ms (inspiration).
Impact: This study demonstrates the feasibility of MR Fingerprinting for 2D T1, T2, and M0 mapping of the lung parenchyma at 0.55T in healthy subjects, which may have future clinical implications for various pulmonary diseases including asthma, emphysema, and cystic fibrosis.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords