Keywords: Low-Field MRI, Low-Field MRI, MR Fingerprinting, T1 Mapping, T2 Mapping, Fat-fraction Quantification
Motivation: Cardiac MRF is a powerful imaging-technique that allows for comprehensive myocardial tissue characterization in a single-scan and has been proposed at 1.5T and 3T. However, cMRF has not been demonstrated at lower-field yet.
Goal(s): Investigate the feasibility of a Dixon-cMRF sequence for simultaneous T1, T2 and fat-fraction quantification at 0.55T.
Approach: Dual-echo spoiled-GRE-acquisition with varying IR-T2-preparation pulses. Experiments were performed on standardized phantoms and with 5 healthy volunteers and compared with spin-echo references.
Results: T1, T2 and fat-fraction Dixon-cMRF at 0.55T was tested with phantoms and with healthy subjects, showing good agreement with reference values in phantom and promising results in healthy subjects.
Impact: The simultaneous quantification of T1, T2 and fat-fraction at 0.55T in a single cardiac-MRF of 15s could provide an alternative to higher field scanners, allowing for a more accessible way to assess cardiovascular disease.
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