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Abstract #2703

Absolute MR Thermometry in the breast using interleaved echo planar spectroscopic imaging

Henrik Odéen1, Peyton Wong1, Duane Blatter1, Seong-Eun Kim1, Allison Payne1, and Dennis L Parker1
1Radiology and Imaging Sciences, University of Utah, Salt Lake City, UT, United States

Synopsis

Keywords: Thermometry/Thermotherapy, Thermometry, Breast, Spectroscopic imaging

Motivation: Clinically available MR thermometry methods only measures relative temperature change. Availability of absolute temperature measurements has high impact potential to improve monitoring and evaluation of thermal therapies.

Goal(s): Develop an efficient and practical approach for spatial absolute MR thermometry in the breast.

Approach: A multi-echo echo-planar spectroscopic imaging pulse sequence was implemented and tested in ex vivo human breast fat samples and healthy volunteers. Comparisons to single voxel spectroscopy was performed.

Results: Water and fat peaks can be detected in both ex vivo samples and in vivo, and converted to absolute temperature measurements. Potential of spatial absolute thermometry is demonstrated.

Impact: Absolute MR thermometry has the potential to improve treatment monitoring and evaluation of thermal therapies, and is demonstrated in the breast using a new efficient high-resolution interleaved echo planar spectroscopic imaging pulse sequence.

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