Keywords: Interventional Devices, Simulations, Brain Tumor, UHF-MRI, Thermal Therapy, Multi-Target Evaluation
Motivation: Thermal Magnetic Resonance (ThermalMR) adds a thermal intervention dimension to MRI by focusing E-fields in the target region (TR). Today’s assessment of RF applicators uses TRs covering a few specific but arbitrary locations in the brain. This approach does not represent the full clinical picture.
Goal(s): This work introduces a multi-target evaluation (MTE) framework and expands RF applicator evaluation to whole brain coverage.
Approach: MTE using EMF simulations for a helmet and for an annular RF applicator.
Results: Our MTE approach provides a technical foundation for the development and objective evaluation of RF applicators tailored for ThermalMR.
Impact: MTE provides a technical foundation for objective RF applicator evaluation using whole brain coverage instead of a few specific but arbitrary target locations. Our framework presents a springboard for RF applicator design and for ThermalMR-based therapy of glioblastoma multiforme.
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