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Abstract #2729

Towards Automated Deep Learning based MR-only Radiation Therapy Planning in <5mins MR Scan Time

Florian Wiesinger1, Sandeep Kaushik1,2, Laszlo Rusko3, Marta Capala4, Iris Lauwers4, Eszter Szabo3, Cristina Cozzini1, Steven Petit4, and Juan Hernandez-Tamames5,6
1GE HealthCare, Munich, Germany, 2University of Zurich, Zurich, Switzerland, 3GE HealthCare, Budapest, Hungary, 4Department of Radiation Oncology, Erasmus MC Cancer Institute, Rotterdam, Netherlands, 5Department of Radiology and Nuclear Medicine, Erasmus MC, Rotterdam, Netherlands, 6Department of Imaging Physics, TU Delft, Delft, Netherlands

Synopsis

Keywords: MR-Guided Radiotherapy, Radiotherapy, Deep Learning, MR-only, Radiation Therapy Planning

Motivation: Deep Learning (DL) is an enabling technology for MR-only Radiation Therapy Planning in terms of 1) MR to synthetic CT conversion and 2) automated Organ-At-Risk (OAR) segmentation.

Goal(s): To investigate the feasibility of DL based MR-only RT planning using accelerated MR protocols with <5mins scan time (not including tumor depiction).

Approach: Quantitative evaluation of synthetic CTs in terms of mean absolute error (MAE) and OAR segmentations in terms of Likert Score analysis.

Results: Preliminary results demonstrate the feasibility of DL-based MR-only RT in <5min scan time with only minor degradation of synthetic CT and OAR segmentation quality.

Impact: Deep Learning is an enabling technology for MR-only Radiation Therapy Planning. Here we demonstrate its capabilities for 1) synthetic CT conversion and 2) Organ-At-Risk (OAR) segmentation in <5min MR scan time.

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