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Abstract #2733

Efficient Standardization of Clinical T2-Weighted Images: Phase-Conjugacy e-CAMP with Projected Gradient Descent

Horace Z. Zhang1, Nahla Elsaid2, Heng Sun1, Hemant Tagare2, and Gigi Galiana1,2
1Department of Biomedical Engineering, Yale University, New Haven, CT, United States, 2Department of Radiology and Biomedical Imaging, Yale University, New Haven, CT, United States

Synopsis

Keywords: Image Reconstruction, Quantitative Imaging

Motivation: Routine clinical images are a massive data source for machine learning. The previously introduced e-CAMP method can convert T2-weighted images of clinical TSE acquisition to quantitative T2 maps, but it requires tuning of many parameters, impeding widespread implementation.

Goal(s): To present an algorithm that requires few parameter choices, is robust to those parameter values, and is faster to convergence.

Approach: Projected Gradient Descent ensures efficient enforcement of the T2-decay model constraint and greatly eliminates parameter tuning. e-CAMP is further enhanced by phase conjugacy with Virtual Conjugate Coils.

Results: The efficient and robust implementation of e-CAMP shows accurate T2 map reconstruction.

Impact: Rather than acquire specific yet time-consuming quantitative images, e-CAMP can efficiently standardize the existing qualitative images from routine clinical scans and exploit the enormous amount of images to create dataset for large-scale machine learning.

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Keywords