Abstract #2766

Oxygen-enhanced Ultrashort Echo Time MRI in Diagnosis of Benign and Malignant Solid Pulmonary Nodules: a preliminary study

Xianqi Wang^1,2,3,4, Jinsha Liu^1,2,3,4, Xingang Wang^1,2, Jing Li^1,2, Shaoxin Xiang⁵, Yuxin Yang⁵, Taotao Yang^1,2,3,4, Meng Zeng^1,2, and Wei Chen^1,2,3,4

¹Department of Radiology, Southwest Hospital, Army Medical University (Third Military Medical University), Chongqing, China, ²7T Magnetic Resonance Imaging Translational Medical Center, Southwest Hospital, Army Medical University (Third Military Medical University), Chongqing, China, ³YuYue Laboratory, Chongqing, China, ⁴Jinfeng Laboratory, Chongqing, China, ⁵MR Collaboration, United Imaging Research Institute of Intelligent Imaging, Beijing, China

Synopsis

Keywords: Lung, Cancer, ultrashort echo time (UTE)；oxygen-enhanced MRI (OE-MRI)

Motivation: People pay more and more attention to the high incidence and mortality of lung cancer.

Goal(s): To develop a non-invasive, radiation-free imaging scheme to distinguish between benign and malignant solid pulmonary nodules and to improve the management of patients with pulmonary nodules.

Approach: Two three-dimensional ultrashort echo time series scans of pulmonary nodules were performed on 3.0T MRI under the condition of 21% and 100% oxygen, respectively, and the percent signal enhancement was used as the evaluation index of benign and malignant nodules.

Results: The increase of the percent signal enhancement in benign pulmonary nodules was higher than that in malignant pulmonary nodules.

Impact: This imaging tool will reduce or eliminate the radiation damage caused by computed tomography, reduce clinicians' over-dependence on high resolution computed tomography, and bring new gospel for personalized and accurate diagnosis and treatment of patients.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.