Abstract #2768

Variability in measurements of abdominal blood flow using non-invasive phase-contrast-mapping MRI

Bryan Haddock¹, Frederikke Østergaard², Rasmus Syberg Rasmussen², Ludvig Schimming Langberg², Lotte Alstrup¹, Tanne S.W Larsson¹, Ali Asmar³, Henrik B.W Larsson⁴, Ulrik Andersen⁴, Lærke Smidt Gasberg², and Mark Bitsch Vestergaard⁴

¹Department of Clinical Physiology and Nuclear Medicine, Department of Clinical Physiology and Nuclear Medicine, Rigshospitalet, Copenhagen University Hospital, Denmark, Glostrup, Copenhagen, Denmark, ²Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark, Copenhagen, Denmark, ³Department of Clinical Physiology and Nuclear Medicine, Bispebjerg and Frederiksberg Hospital, University Hospital of Copenhagen, Copenhagen, Denmark, Copenhagen, Denmark, ⁴Department of Clinical Physiology and Nuclear Medicine, Department of Clinical Physiology and Nuclear Medicine, Rigshospitalet, Copenhagen University Hospital, Denmark, Copenhagen, Denmark

Synopsis

Keywords: Digestive, Digestive, PC-MRI, Intestine

Motivation: Measuring the reproducibility of 2D PC-MRI measures of intestinal blood flow is important for its clinical application.

Goal(s): The aim is to examine the precision of 2D PC-MR measures of resting intestinal blood flow and postprandial blood flow changes.

Approach: Ten healthy men were scanned on eight different days collecting at least three repeated 2D PC-MRI measures each day. Participants were also given an oral glucose tolerance test.

Results: A CoV of 6%-9% was obtained for consecutive flow measures and 13%-15% for between day measurements. Flow increased 75% in the arteria mesenterica superior and 60% in the vena portae after glucose consumption.

Impact: The low variability of repeated flow measures in the arteria mesenterica superior and vena portae compared to the high change in flow after glucose consumption makes 2D PC-MRI measures of flow changes in these vessels a feasible diagnostic test.

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