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Abstract #2767

Pulmonary Perfusion via Magnetic Resonance Imaging is Associated with hospitalization for COVID-19

Shadi Afyouni1, Andy Lancaster2, Ghazal Zandieh1, Chikara Noda1, Yoko Kato1, Chia-Ying Liu3, Yoshimori Kassai4, Joao Lima1, and Bharath Ambale Venkatesh1
1Johns Hopkins University, Baltimore, MD, United States, 2Johns Hopkins University, Ba, MD, United States, 3Canon Medical Systems, Baltimore, MD, United States, 4Canon Medical Systems, Tokyo, Japan

Synopsis

Keywords: Lung, COVID-19, Lung

Motivation: COVID-19's persistent respiratory effects are well-documented, but the long-term pulmonary consequences, particularly after severe illness, remain inadequately understood.

Goal(s): To identify enduring perfusion deficits in the lungs of individuals previously hospitalized with COVID-19, using dynamic contrast-enhanced (DCE) MRI.

Approach: The study recruited adults post-COVID-19 for a comprehensive pulmonary assessment. Dynamic contrast enhanced MRI was used to quantify lung perfusion and relating them to COVID-related hospitalization.

Results: The study found a significant correlation between MRI perfusion parameters and previous hospitalization for COVID-19. It indicated that patients with a history of hospitalization due to COVID-19 might experience persistent alterations in lung perfusion.

Impact: Our research, through dynamic contrast-enhanced MRI, reveals persisting lung perfusion deficits in post-hospitalized COVID-19 patients, notably related to severity of initial disease. This aids in understanding post-COVID pulmonary sequelae, guiding future patient management and research on long-term COVID-19 impact.

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Keywords